論文

  1. The sodium phosphate cotransporter family and nicotinamide phosphoribosyltransferase contribute to the daily oscillation of plasma inorganic phosphate concentration.
    Miyagawa, A; Tatsumi, S; Takahama, W; Fujii, O; Nagamoto, K; Kinoshita, E; Nomura, K; Ikuta, K; Fujii, T; Hanazaki, A; Kaneko, I; Segawa, H; Miyamoto, KI.
    Kidney Int. 93(5): p1073-1085, 2018
  2. Effect of Osteocyte-Ablation on Inorganic Phosphate Metabolism: Analysis of Bone-Kidney-Gut Axis.
    Fujii, O; Tatsumi, S; Ogata, M; Arakaki, T; Sakaguchi, H; Nomura, K; Miyagawa, A; Ikuta, K; Hanazaki, A; Kaneko, I; Segawa, H; Miyamoto, KI.
    Front Endocrinol (Lausanne). 8(359). 2017
  3. Effect of Npt2b deletion on intestinal and renal inorganic phosphate (Pi) handling.
    Ikuta, K; Segawa, H; Sasaki, S; Hanazaki, A; Fujii, T; Kushi, A; Kawabata, Y; Kirino, R; Sasaki, S; Noguchi, M; Kaneko, I; Tatsumi, S; Ueda, O; Wada, NA; Tateishi, H; Kakefuda, M; Kawase, Y; Ohtomo, S; Ichida, Y; Maeda, A; Jishage, KI; Horiba, N; Miyamoto, KI.
    Clin Exp Nephrol. https://doi.org/10.1007/s10157-017-1497-3, 2017
  4. Effect of Osteocyte-Ablation on Inorganic Phosphate Metabolism: Analysis of Bone-Kidney-Gut Axis.
    Fujii, O; Tatsumi, S; Ogata, M; Arakaki, T; Sakaguchi, H; Nomura, K; Miyagawa, A; Ikuta, K; Hanazaki, A; Kaneko, I; Segawa, H; Miyamoto, KI.
    Front Endocrinol (Lausanne). 8(359). 2017
  5. Relationship between sodium-dependent phosphate transporter (NaPi-IIc) function and cellular vacuole formation in opossum kidney cells.
    Shiozaki Yuji; Segawa Hiroko; Ohnishi Saori; Ohi Akiko; Ito Mikiko; Kaneko Ichiro; Kido Shinsuke; Tatsumi, Sawako; Miyamoto Ken-ichi
    J Med Invest 62(3-4): p209-218, 2015
  6. Molecular mechanisms of cadmium-induced fibroblast growth factor 23 upregulation in osteoblast-like cells.
    Kido, Shinsuke; Fujihara, Marina; Nomura, Kengo; Sasaki, Shohei; Mukai, Rie; Ohnishi, Ritsuko; Kaneko, Ichiro; Segawa, Hiroko; Tatsumi, Sawako; Izumi, Hiroto; Kohno, Kimitoshi; Miyamoto, Ken-ichi
    Toxicol Sci 139(2): p301-316, 2014
  7. Hepatectomy-related hypophosphatemia: a novel phosphaturic factor in the liver-kidney axis.
    Nomura, Kengo; Tatsumi, Sawako; Miyagawa, Atsumi; Shiozaki, Yuji; Sasaki, Shohei; Kaneko, Ichiro; Ito, Mikiko; Kido, Shinsuke; Segawa, Hiroko; Sano, Mitsue; Fukuwatari, Tsutomu; Shibata, Katsumi; Miyamoto, Ken-ichi
    J Am Soc Nephrol 25(40): p761-772, 2014
  8. Effect of dietary components on renal inorganic phosphate (Pi) excretion induced by a Pi-depleted diet.
    Ohnishi, Ritsuko; Segawa, Hiroko; Ohmoto, Tomoyo; Sasaki, Shohei; Hanazaki, Ai; Mori, Ayaka; Ikuta, Kayo; Furutani, Junya; Kawakami, Eri; Tatsumi, Sawako; Hamada, Yasuhiro; Miyamoto, Ken-ichi
    J Med Invest 61(1-2): p162-170, 2014
  9. Histological examination on osteoblastic activities in the alveolar bone of transgenic mice with induced ablation of osteocytes.
    Li, Minqi; Hasegawa, Tomoka; Hogo, Hiromi; Tatsumi, Sawako; Liu, Zhusheng; Guo, Ying; Sasaki, Muneteru; Tabata, Chihiro; Yamamoto, Tsuneyuki; Ikeda, Kyoji; Amizuka, Norio
    Histol Histopathol 28(3): p327-335, 2013
  10. Processing and stability of type II sodium-dependent phosphate cotransporter mutations in patients with hereditary hypophosphatemic rickets with hypercalciuria.
    Haito-Sugino, Sakiko; Ito, Mikiko; Ohi, Akiko; Shiozaki, Yuji; Kangawa, Natsumi; Nishiyama, Takashi; Aranami, Fumito; Sasaki, Shohei; Mori, Ayaka; Kido, Shinsuke; Tatsumi, Sawako; Segawa, Hiroko; Miyamoto, Ken-ichi
    Am J Physiol Cell Physiol 302(9): C1316-30, 2012
  11. Identification and functional analysis of splice variant of mouse sodium-dependent phosphate transporter Npt2c.
    Kuwahara, Shoji; Aranami, Fumito; Segawa, Hiroko; Onitsuka, Akemi; Honda, Naoko; Tominaga, Rieko; Hanabusa, Etsuyo; Kaneko, Ichiro; Yamanaka, Setsuko; Sasaki, Shohei; Ohi, Akiko; Nomura, Kengo; Tatsumi, Sawako; Kido, Shinsuke; Ito, Mikiko; Miyamoto, Ken-ichi
    J Med Invest 59(1-2): p116-126, 2012
  12. Inorganic phosphate homeostasis in sodium-dependent phosphate co-transporter Npt2b+/- mice
    Ohi, Akiko; Hanabusa, Etsuyo; Ueda, Otoya; Segawa, Hiroko; Horiba, Naoshi; Kaneko, Ichiro; Kuwahara, Shoji; Mukai, Tomo; Sasaki, Shohei; Tominaga, Rieko; Furutani, Junya; Aranami, Fumito; Ohtomo, Shuichi; Oikawa, Yumiko; Kawase, Yousuke; Wada, Naoko A.; Tachibe, Takanori; Kakefuda, Mami; Tateishi, Hiromi; Matsumoto, Kaoru; Tatsumi, Sawako; Kido, Shinsuke; Fukushima, Naoshi; Jishage, Kou-ichi; Miyamoto, Ken-ichi
    Am J Physiol Renal Physiol 301(5): F1105-1113, 2011
  13. Fibroblast growth factor 23 mediates the phosphaturic actions of cadmium
    Aranami, Fumito; Segawa, Hiroko; Furutani, Junya; Kuwahara, Shoji; Tominaga, Rieko; Hanabusa, Etsuyo; Tatsumi, Sawako; Kido, Shinsuke; Ito, Mikiko; Miyamoto, Ken-Ichi
    J Med Invest 57(1): p95-108., 2010
  14. An apical expression signal of the renal type IIc Na+-dependent phosphate cotransporter in renal epithelial cells.
    Ito, Mikiko; Sakurai, Aya; Hayashi, Keiji; Ohi, Akiko; Kangawa, Natsumi; Nishiyama, Takashi; Sugino, Sakiko; Uehata, Yoko; Kamahara, Akihiro; Sakata, Masae; Tatsumi, Sawako; Kuwahata, Masashi; Taketani, Yutaka; Segawa, Hiroko; Miyamoto, Ken-ichi
    Am J Physiol Renal Physiol 299(1): F243-254, 2010
  15. Phosphaturic action of fibroblast growth factor 23 in Npt2 null mice.
    Tomoe, Yuka; Segawa, Hiroko; Shiozawa, Kazuyo; Kaneko, Ichiro; Tominaga, Rieko; Hanabusa, Etsuyo; Aranami, Fumito; Furutani, Junya; Kuwahara, Shoji; Tatsumi, Sawako; Matsumoto, Mitsutu; Ito, Mikiko; Miyamoto, Ken-ichi
    Am J Physiol Renal Physiol 298(6): F1341-1350, 2010
  16. Life-long caloric restriction reveals biphasic and dimorphic effects on bone metabolism in rodents.
    Tatsumi, Sawako; Ito, Masako; Asaba, Yutaro; Tsutsumi, Kumi; Ikeda, Kyoji
    Endocrinology 149(2): p634-641, 2008
  17. Localization of polypyrimidine-tract-binding protein is involved in the regulation of albumin synthesis by branched-chain amino acids in HepG2 cells.
    Kuwahata, Masashi; Yoshimura, Tomoyo; Sawai, Yukiko; Amano, Saki; Tomoe, Yuka; Segawa, Hiroko; Tatsumi, Sawako; Ito, Mikiko; Ishizaki, Sonoko; Ijichi, Chiori; Sonaka, Ichiro; Oka, Tatsuzo; Miyamoto, Ken-ichi
    J Nutr Biochem 19(7): p438-447, 2008
  18. Characterization of the molecular mechanisms involved in the increased insulin secretion in rats with acute liver failure.
    Kuwahata, Masashi; Tomoe, Yuka; Harada, Nagakatsu; Amano, Saki; Segawa, Hiroko; Tatsumi, Sawako; Ito, Mikiko; Oka, Tatsuzo; Miyamoto, Ken-ichi
    Biochim Biophys Acta 1772(1): p60-65, 2007
  19. Unique uptake and efflux systems of inorganic phosphate in osteoclast-like cells.
    Ito, Mikiko; Haito, Sakiko; Furumoto, Mari; Uehata, Yoko; Sakurai, Aya; Segawa, Hiroko; Tatsumi, Sawako; Kuwahata, Masashi; Miyamoto, Ken-ichi
    Am J Physiol-Cell Physiol 292(1): C526-534, 2007
  20. Overexpression of gamma-glutamyltransferase in transgenic mice accelerates bone resorption and causes osteoporosis.
    Hiramatsu, Kiyoshi; Asaba, Yutaro; Takeshita, Sunao; Nimura, Yuji; Tatsumi, Sawako; Katagiri, Nobuyoshi; Niida, Shumpei; Nakajima, Toshihiro; Tanaka, Sakae; Ito, Masako; Karsenty, Gerard; Ikeda, Kyoji
    Endocrinology 148(6): p2708-2715, 2007
  21. Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction.
    Tatsumi, Sawako; Ishii, Kiyoaki; Amizuka, Norio; Li, Minqi; Kobayashi, Toshihiro; Kohno, Kenji; Ito, Masako; Takeshita, Sunao; Ikeda, Kyoji
    Cell Metab 5(6): p464-475, 2007
  22. Control of phosphate appetite in young rats
    Ohnishi, Ritsuko; Segawa, Hiroko; Kawakami, Eri; Furutani, Junya; Ito, Mikiko; Tatsumi, Sawako; Kuwahata, Masashi; Miyamoto, Ken-Ichi
    J Med Invest 54(3-4): p366-369, 2007
  23. Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation.
    Trembley, JH; Tatsumi, S; Sakashita, E; Loyer, P; Slaughter, CA; Suzuki, H; Endo, H; Kidd, VJ; Mayeda, A
    Mol Cell Biol 25(4): p1446-1457, 2005
  24. Human RNPS1 and its associated factors: a versatile alternative pre-mRNA splicing regulator in vivo.
    Sakashita, E; Tatsumi, S; Werner, D; Endo, H; Mayeda, A
    Mol Cell Biol 24(3): p1174-1187, 2004
  25. Growth-related renal type II Na/Pi cotransporter.
    Segawa, H; Kaneko, I; Takahashi, A; Kuwahata, M; Ito, M; Ohkido, I; Tatsumi, S; Miyamoto, K
    J Biol Chem 277(22): p19665-19672, 2002
  26. Nicotinamide inhibits sodium-dependent phosphate cotransport activity in rat small intestine
    Katai, K; Tanaka, H; Tatsumi, S; Fukunaga, Y; Genjida, K; Morita, K; Kuboyama, N; Suzuki, T; Akiba, T; Miyamoto, K; Takeda, E
    Nephrol Dial Transplant 14: p19745-19751, 1999
  27. Regulation of intestinal Na+- dependent phosphate co-transporters by a low-phosphate diet and 1,25-dihydroxyvitamin D3
    Katai, K; Miyamoto, K; Kishida, S; Segawa, H; Nii, T; Tanaka, H; Tani, Y; Arai, H; Tatsumi, S; Morita, K; Taketani, Y; Takeda, E
    Biochem J 343(3) p705-712, 1999
  28. Effect of dietary phosphate on the sodium-dependent phosphate transporter (NaPi-2) in rat kidney
    Katai K; Miyamoto K; Segawa H; Haga H; Morita K; Arai H; Tatsumi, S; Taketani Y; Hisano S; Fukui Y; Takahashi F; Ono A; Takeda E.
    J Develop Nephrol 6: p38-47, 1998
  29. Characterization of the 5flanking region of the human NPT-1 Na+/Phosphate cotransporter gene.
    Taketani, Y; Miyamoto, K; Chikamori, M; Tanaka, K; Yamamoto, H; Tatsumi, S; Morita, K; Takeda, E
    Biochim Biophys Acta 1396: p267-272, 1998
  30. Molecular cloning and hormonal regulation of PiT-1 a sodium-dependent phosphate cotransporter from rat parathyroid glands
    Tatsumi, S; Segawa, H; Morita, K; Haga, H; Kouda, T; Yamamoto, H; Inoue, Y; Nii, T; Katai, K; Taketani, Y; Miyamoto, KI; Takeda, E
    Endocrinology 139(3): p1692-1699, 1998
  31. Effect of Dietary Phosphate on Na+ - Phosphate Cotransporters Function and Expression in the Rat Kidney
    Morita K; Haga H; Tanaka H; Fujioka A; Segawa H; Katai K; Tatsumi, S; Koda T; Taketani Y; Hisano S; Fukui Y; Miyamoto K; Takeda E
    Clin Expe Nephrol 2(2): p109-116, 1998
  32. Regulation of type II renal Na+-dependent inorganic phosphate transporters by 1,25-dihydroxyvitamin D3
    Taketani, Y; Segawa, H; Chikamori, M; Morita, K; Tanaka, K; Kido, S; Yamamoto, H; Iemori, Y; Tatsumi, S; Tsugawa, N; Okano, T; Kobayashi, T; Miyamoto, K; Takeda, E
    J Biol Chem. 27(23): p109-116, 1998
  33. Effects of dietary Pi on the renal Na+-dependent Pi transporter NaPi-2 in thyroparathyroidectomized rats
    Takahashi, F; Morita, K; Katai, K; Segawa, H; Fujioka, A; Kouda, T; Tatsumi, S; Nii, T; Taketani, Y; Haga, H; Hisano, S; Fukui, Y; Miyamoto, K; Takeda, E
    Biochem J 333(1): p111-113, 1998
  34. Identification of three isoforms for the Na+-dependent phosphate cotransporter(NaPi-2) in rat kidney
    Tatsumi, S; Miyamoto, K; Kouda, T; Motonaga, K; Katai, K; Ohkido, I; Morita, K; Segawa, H; Tani, Y; Yamamoto, H; Taketani, Y; Takeda, E
    J Biol Chem 273(44): p354-362, 1998
  35. Acute regulation by dietary phosphate of the sodium-dependent phosphate transporter (NaPi-2) in rat kidney
    Katai, K; Segawa, H; Haga, H; Morita, K; Arai, H; Tatsumi, S; Taketani, Y; Miyamoto, K; Hisano, S; Fukui, Y; Takeda, E
    J Biochem 121(1): p50-55, 1997
  36. Gene structure and functional analysis of the human Na+/phosphate co-transporter (NaPi-3)
    Taketani, Y; Miyamoto, K; Tanaka, K; Katai, K; Chikamori, M; Tatsumi, S; Segawa, H; Yamamoto, H; Morita, K; Takeda, E
    Biochem J 324(3): p927-934, 1997
  37. Structural organization of the human vitamin D receptor chromosomal gene and its promotor
    Miyamoto, K; Kesterson, RA; Yamamoto, H; Taketani, Y; Nishiwaki, E; Tatsumi, S; Inoue, Y; Morita, K; Takeda, E; Pike, JW
    Mol Endocrinol 11(8): p1165-1179, 1997
  38. Immunohistochemical and RT-PCR detection of Na+-dependent inorganic phosphate cotransporter (NaPi-2) in rat brain.
    Hisano, S; Haga, H; Li, ZN; Tatsumi, S; Miyamoto, K; Takeda, E; Fukui, Y
    Brain Reserch 772(1-2): p149-155, 1997
  39. Relative contributions of Na+-dependent phosphate co-transporters to phosphate transport in mouse kidney: RNase H-mediated hybrid depletion analysis
    Miyamoto, K; Segawa, H; Morita, K; Nii, T; Tatsumi, S; Taketani, Y; Takeda, E
    Biochem J 358(3): p693-704, 1997
  40. Cloning, functional expression and dietary regulation of the mouse neutral and basic amino acid transporter (NBAT)
    Segawa, H; Miyamoto, K; Ogura, Y; Haga, H; Morita, K; Katai, K; Tatsumi, S; Nii, T; Taketani, Y; Takeda, E
    Biochem J 328: p657-664, 1997
  41. Effects of truncation of the COOH-terminal region of a Na+-independent neutral and basic amino acid transporter on amino acid transport in Xenopus oocytes
    Miyamoto, K; Segawa, H; Tatsumi, S; Katai, K; Yamamoto, H; Taketani, Y; Haga, H; Morita, K; Takeda, E
    J Biol Chem 271(28): p16758-16763, 1996
  42. Cloning and functional expression of a Na+-dependent phosphate cotransporter from human: cDNA cloning and functional expression
    MIYAMOTO, KI; Tatsumi, S; SONODA, T; YAMAMOTO, H; MINAMI, H; TAKETANI, Y; TAKEDA, E
    Biochem J 305(1): p81-85, 1995
  43. Chromosome assignments of gene for human Na+-dependent phosphate co-transporter NaPi-3 and NPT-1
    Miyamoto, Ken-Ichi; Tatsumi, Sawako; Yamamoto, Hironori; Katai, Kanako; Taketani, Yutaka; Morita, Kyoko; Takeda, Eiji
    Tokushima J Exp Med 42(1-2): p5-9, 1995
  44. Mutations of the basic amino acid transporter gene associated with cystiuria.
    MIYAMOTO, K; KATAI, K; Tatsumi, S; SONE, K; SEGAWA, H; YAMAMOTO, H; TAKETANI, Y; TAKADA, K; MORITA, K; KANAYAMA, H; KAGAWA, S; TAKEDA, E
    Biochm J 310(3): p951-955, 1995
  45. Characterization of the rabbit intestinal fructose transporter (GLUT5)
    MIYAMOTO, K; Tatsumi, S; MORIMOTO, A; MINAMI, H; YAMAMOTO, H; SONE, K; TAKETANI, Y; NAKABOU, Y; OKA, T; TAKEDA, E
    Biochem J 303(3): p877-883, 1994
    46.

総説

  1. Control of phosphate balance by the kidney and intestine
    Kaneko, Ichiro; Tatsumi, Sawako; Segawa, Hiroko; Miyamoto, Ken-ichi
    Clin Exp Nephrol 21(Suppl 1): p21-26, 2017
  2. Regulation of renal phosphate handling: inter-organ communication in health and disease
    Tatsumi, Sawako; Miyagawa, Atsumi; Kaneko, Ichiro; Shiozaki, Yuji; Segawa, Hiroko; Miyamoto, Ken-ichi
    J Bone Miner Metab 34(1): p1-10 , 2016
  3. Niacin and Chronic Kidney Disease.
    Taketani, Yutaka; Masuda, Masashi; Yamanaka-Okumura, Hisami; Tatsumi, Sawako; Segawa, Hiroko; Miyamoto, Ken-ichi; Takeda, Eiji; Yamamoto, Hironori
    J Nutr Sci Vitaminol (Tokyo) 61 Suppl: S173-175, 2015
  4. Vitamin D and type II sodium-dependent phosphate cotransporters.
    Kido, Shinsuke; Kaneko, Ichiro; Tatsumi, Sawako; Segawa, Hiroko; Miyamoto, Ken-ichi; Razzaque, MS
    Contrib Nephrol 180: p86-97, 2013
  5. Sodium-dependent phosphate cotransporters: lessons from gene knockout and mutation studies.
    Miyamoto, Ken-Ichi; Haito-Sugino, Sakiko; Kuwahara, Shoji; Ohi, Akiko; Nomura, Kengo; Ito, Mikiko; Kuwahata, Masashi; Kido, Shinsuke; Tatsumi, Sawako; Kaneko, Ichiro; Segawa, Hiroko
    J Pharm Sci 100(9): p3719-3730 , 2011
  6. New aspect of renal phosphate reabsorption: the type IIc sodium-dependent phosphate transporter
    Miyamoto, Ken-Ichi; Ito, Mikiko; Tatsumi, Sawako; Kuwahata, Masashi; Segawa, Hiroko
    Am J Nephrol 27(5): p503-515, 2007
  7. Regulation of PiT-1, a sodium-dependent phosphate co-transporter in rat parathyroid glands.
    Miyamoto K; Tatsumi S; Segawa H; Morita K; Nii T; Fujioka A; Kitano M; Inoue Y; Takeda E
    Nephrol Dial Transplant 14 (suppl 1): p73-75 , 1999
  8. Does the parathyroid 'see' phosphate?
    Miyamoto, K; Tatsumi, S; Morita, K; Takeda, E
    Nephrol Dial Transplant 13(11): p2727-2729, 1998
    9.